TRPS1 CLIA Kit for Human(Homo sapiens) | EIAab.comTRPS1 CLIA Kit for Human(Homo sapiens)

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TRPS1 (Gene name),

Zinc finger transcription factor Trps1 (Protein name ), TRPS1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

TRPS1;

Protein name:

Zinc finger transcription factor Trps1;

Alternative:

Zinc finger protein GC79;Tricho-rhino-phalangeal syndrome type I protein;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with RNF4; regulates TRPS1 repressor activity. Interacts specifically with the activator form of GLI3 (GLI3A) but not with the repressor form (GLI3R).

Function:

Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

1281

Sequence:

50:

100:

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300:

350:

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1050:

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1150:

1200:

1250:

1281:

LCTDKYDFTT | HIQRGLHRNN | AQVEKNGKPK | E

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

MIM:

150230

SMR:

Q9UHF7

UniGene:

Hs.657018

STRING:

9606.ENSP00000379065

Pfam:

PF00320

KEGG:

hsa:7227

String:

Q9UHF7

Uniprot:

Q9UHF7

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ELISA Kit for Human Zinc finger transcription factor Trps1

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E3470h

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Packing:

96T

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ELISA Kit for Human Zinc finger transcription factor Trps1

Cat.:

E3470m

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MSDS:

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Packing:

96T

CLIA Kit for Human Zinc finger transcription factor Trps1

Cat.:

U3470m

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MSDS:

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Packing:

96T

CLIA Kit for Human Zinc finger transcription factor Trps1

Cat.:

U3470h

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Zinc finger transcription factor Trps1

Cat.:

P3470Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Zinc finger transcription factor Trps1

Cat.:

P3470Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Zinc finger transcription factor Trps1

Protein for Human Zinc finger transcription factor Trps1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Mutations in a new gene, encoding a zinc-finger protein, cause tricho-rhino-phalangeal syndrome type I."
Momeni P. , Gloeckner G. , Schmidt O. , von Holtum D. , Albrecht B. , Gillessen-Kaesbach G. , Hennekam R.C.M. , Meinecke P. , Zabel B. , Rosenthal A. , Horsthemke B. , Luedecke H.-J.
Nat. Genet.24:71-74(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
2.

"Characterization of a zinc-finger protein and its association with apoptosis in prostate cancer cells."
Chang G.T.G. , Steenbeek M. , Schippers E. , Blok L.J. , van Weerden W.M. , van Alewijk D.C.J.G. , Eussen B.H.J. , van Steenbrugge G.J. , Brinkmann A.O.
J. Natl. Cancer Inst.92:1414-1421(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Prostate.
3.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 495-1281 (ISOFORM 1)
tissue: Embryo.
tissue: Trachea.
4.

"DNA sequence and analysis of human chromosome 8."
Nusbaum C. , Mikkelsen T.S. , Zody M.C. , Asakawa S. , Taudien S. , Garber M. , Kodira C.D. , Schueler M.G. , Shimizu A. , Whittaker C.A. , Chang J.L. , Cuomo C.A. , Dewar K. , FitzGerald M.G. , Yang X. , Allen N.R. , Anderson S. , Asakawa T. , more...
Nature439:331-335(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
6.

"The RING finger protein RNF4, a co-regulator of transcription, interacts with the TRPS1 transcription factor."
Kaiser F.J. , Moeroey T. , Chang G.T. , Horsthemke B. , Luedecke H.J.
J. Biol. Chem.278:38780-38785(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH RNF4;SUBCELLULAR LOCATION
7.

"Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1085;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
8.

"SUMOylation modulates transcriptional repression by TRPS1."
Kaiser F.J. , Ludecke H.J. , Weger S.
Biol. Chem.388:381-390(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUMOYLATION AT LYS-1192 AND LYS-1201;FUNCTION;MUTAGENESIS OF LYS-1192 AND LYS-1201
9.

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
10.

"Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3."
Wuelling M. , Kaiser F.J. , Buelens L.A. , Braunholz D. , Shivdasani R.A. , Depping R. , Vortkamp A.
Dev. Biol.328:40-53(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GLI3
11.

"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-751; SER-1041 AND SER-1085;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
12.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.

"Genotypic and phenotypic spectrum in tricho-rhino-phalangeal syndrome types I and III."
Luedecke H.-J. , Schaper J. , Meinecke P. , Momeni P. , Gross S. , von Holtum D. , Hirche H. , Abramowicz M.J. , Albrecht B. , Apacik C. , Christen H.-J. , Claussen U. , Devriendt K. , Fastnacht E. , Forderer A. , Friedrich U. , Goodship T.H.J. , Greiwe M. , more...
Am. J. Hum. Genet.68:81-91(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TRPS3 ASP-894; PRO-901; GLN-908; PRO-908 AND THR-919
14.

"Missense mutation of TRPS1 in a family of tricho-rhino-phalangeal syndrome type III."
Kobayashi H. , Hino M. , Shimodahira M. , Iwakura T. , Ishihara T. , Ikekubo K. , Ogawa Y. , Nakao K. , Kurahachi H.
Am. J. Med. Genet.107:26-29(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT TRPS3 GLN-908
15.

"Novel missense mutations in the TRPS1 transcription factor define the nuclear localization signal."
Kaiser F.J. , Brega P. , Raff M.L. , Byers P.H. , Gallati S. , Kay T.T. , de Almeida S. , Horsthemke B. , Luedecke H.-J.
Eur. J. Hum. Genet.12:121-126(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TRPS1 CYS-952 AND HIS-952;CHARACTERIZATION OF VARIANTS TRPS1 CYS-952 AND HIS-952

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